高峰,男,46岁,天津大学英才教授、博导,系统生物工程教育部重点实验室副主任,天津大学生物信息中心主任,合成生物技术全国重点实验室PI,师从生物信息学家张春霆院士攻读硕士、博士学位。主要从事微生物基因组生物信息学与合成生物学研究,已在Science等刊物发表SCI论文100篇(ESI高被引论文8篇,热点论文2篇),获Google Scholar 5400 余次引用,h 指数35(SCI引用4200余次),并被140余本国际英文书籍所引用。其中,第一(通讯)作者SCI论文76篇(影响因子3以上刊物论文69篇),包括Nucleic Acids Research(7)、Briefings in Bioinformatics(11)和Bioinformatics(7)系列25篇;唯一第一(通讯)作者论文57篇(包括Nucleic Acids Research 5篇, PNAS, iMeta, JACS Au, Genomics Proteomics & Bioinformatics, Briefings in Bioinformatics 8篇, Bioinformatics 7篇,Journal of Infection 3篇);双通讯(17篇)和双共一(2篇)SCI论文19篇(包括Nucleic Acids Research 2篇, Briefings in Bioinformatics 3篇, Genomics Proteomics & Bioinformatics, BMC Biology)。作为第一(通讯)作者先后为Springer出版社的Methods in Molecular Biology系列丛书撰写了两个章节,作为客座主编/编辑出版专刊书籍四本。第一(通讯)作者论文SCI引用1900余次(有10篇SCI引用超过50次,4篇超过100次),获Nature、Science、Cell等期刊论文引用并佐证,相关成果得到中央电视台、《科技日报》、《人民日报》等国家级媒体报道,以及90余本国际英文专著、教材、辞典、百科全书等引用。从2007年参加工作以来一直从事基因组复制起始点的相关研究,系统建立和发展了细菌(含质粒)、古菌、真核基因组复制起始点预测软件和数据库。其中,原核基因组复制起始点系列预测软件Ori-Finder(单篇最高SCI引用230余次,曾入选ESI高被引论文)以及数据库DoriC(单篇最高SCI引用100余次)累计SCI引用600余次。Ori-Finder已经成功应用于Cell (Hackl et al., Cell, 2023)、Nature (Graf et al., Nature, 2021)、Nature Microbiology(Needham et al., Nature Microbiology, 2022)等刊物发表新测序基因组的复制起始点预测。美国科学院院士、美国工程院院士、哈佛医学院遗传学系教授George M. Church 课题组在Nature Reviews Methods Primers的综述论文中,推荐Ori-Finder作为复制?。╮eplichore)识别的工具 (Wannier et al., Nature Reviews Methods Primers, 2021)。以色列威茨曼研究所的Eran Segal教授课题组(Korem et al., Science, 2015) 发现,基于宏基因组测序分析的结果与DoriC数据库中关于上百株肠道微生物复制起始点的预测结果具有高度一致性 (R2 = 0.98, P < 10?30)。英国纽卡斯尔大学的Heath Murray教授课题组在模式生物枯草芽孢杆菌的研究中发现,位于染色体复制起始点解旋区的重复性三核苷酸基序(DnaA-trios)是复制起始蛋白DnaA打开DNA双螺旋所必需的元件,普遍存在于DoriC数据库代表性物种预测复制起始点内(Richardson et al., Nature, 2016)。先后主持基因组复制起始点相关的国家自然科学基金项目(5项)、国家重点研发计划课题(课题经费1091万)。
Web of Science: https://www.webofscience.com/wos/author/record/1506509
ORCID: http://orcid.org/0000-0002-9563-3841
Google scholar: http://scholar.google.com/citations?user=_jqaatIAAAAJ&hl=en
ResearcherID: http://www.researcherid.com/rid/C-9913-2009
Publication as Corresponding Author:
1. Huang, H, Yang, Z-L, Wu, X-M, Wang, Y, Liu, Y-J, Luo, H, Lv, X, Gan, Y-R, Song, S-D, Gao, F*: Complete genome sequence of Acinetobacter baumannii MDR-TJ and insights into its mechanism of antibiotic resistance. Journal of Antimicrobial Chemotherapy 2012, 67(12):2825-2832 (被Clinical Infectious Diseases、Gut Microbes等杂志SCI引用63次).
2. Gao, F*, Luo, H, Zhang, C-T*: DoriC 5.0: an updated database of oriC regions in both bacterial and archaeal genomes. Nucleic Acids Research 2013, 41(D1):D90-D93 (被Cell,Science,Nature,Nature Biotechnology, Nature methods等杂志SCI引用107次).
3. Gao, F*: Recent Advances in the identification of replication origins based on the Z-curve method. Current Genomics 2014, 15(2):104-112 (被The ISME Journal等杂志SCI引用17次).
4. Huang, H, Dong, Y, Yang, ZL, Luo, H, Zhang, X, Gao, F*: Complete sequence of pABTJ2, a plasmid from Acinetobacter baumannii MDR-TJ, carrying many phage-like elements. Genomics, Proteomics & Bioinformatics 2014, 12(4):172-177 (被Genome Biology等杂志SCI引用20次).
5. Luo, H, Zhang, C-T*, Gao, F*: Ori-Finder 2, an integrated tool to predict replication origins in the archaeal genomes. Frontiers in Microbiology 2014, 5:482 (被Microbiome、Nature Communications等杂志SCI引用71次).
6. Peng, C, Gao, F*: Protein localization analysis of essential genes in prokaryotes. Scientific Reports 2014, 4:6001 (被PNAS、Briefings in Bioinformatics等杂志SCI引用48次).
7. Gao, F*: Bacteria may have multiple replication origins. Frontiers in Microbiology 2015, 6:324 (被Annual Review of Microbiology, Nature Communications等杂志SCI引用17次).
8. Huang, H, Song, C-C, Yang, Z-L, Dong, Y, Hu, Y-Z, Gao, F*: Identification of the replication origins from Cyanothece ATCC 51142 and their interactions with the DnaA protein: from in silico to in vitro studies. Frontiers in Microbiology 2015, 6:1370.
9. Jia, N, Du, J, Ding, M-Z, Gao, F*, Yuan, Y-J*: Genome sequence of Bacillus endophyticus and analysis of its companion mechanism in the Ketogulonigenium vulgare-Bacillus strain consortium. PLoS ONE 2015, 10(8):e0135104 (被Biotechnology advances等杂志SCI引用19次).
10. Peng, C, Luo, H, Zhang, X, Gao, F*: Recent advances in the genome-wide study of DNA replication origins in yeast. Frontiers in Microbiology 2015, 6:117 (SCI引用19次).
11. Zhang, X, Peng, C, Zhang, G, Gao, F*: Comparative analysis of essential genes in prokaryotic genomic islands. Scientific Reports 2015, 5:12561 (SCI引用10次).
12. Gao, F*: Editorial: DNA replication origins in microbial genomes. Frontiers in Microbiology 2016, 6:1545 (SCI引用3次).
13. Jia, N, Ding, M-Z*, Du, J, Pan, C-H, Tian, G, Lang, J-D, Fang, J-H, Gao, F*, Yuan, Y-J: Insights into mutualism mechanism and versatile metabolism of Ketogulonicigenium vulgare Hbe602 based on comparative genomics and metabolomics studies. Scientific Reports 2016, 6:23068 (被Biotechnology advances等杂志SCI引用21次).
14. Jia, N, Ding, M-Z*, Gao, F*, Yuan, Y-J: Comparative genomics analysis of the companion mechanisms of Bacillus thuringiensis Bc601 and Bacillus endophyticus Hbe603 in bacterial consortium. Scientific Reports 2016, 6:28794 (SCI引用15次).
15. Jia, N, Ding, M-Z*, Du, Y-Z, Feng, S, Gao, F*, Yuan, Y-J: Complete genome sequence of the industrial bacterium Ketogulonicigenium vulgare SKV. Genome Announc 2016, 4(6):e01426-16 (SCI引用5次).
16. Jia, N, Ding, M-Z*, Luo, H, Gao, F*, Yuan, Y-J: Complete genome sequencing and antibiotics biosynthesis analysis of Streptomyces lydicus 103. Scientific Reports 2017, 7:44786 (SCI引用15次).
17. Jia, N, Ding, M-Z*, Zou, Y, Gao, F*, Yuan, Y-J: Comparative genomics and metabolomics analyses of the adaptation mechanism in Ketogulonicigenium vulgare-Bacillus thuringiensis consortium. Scientific Reports 2017, 7:46759 (被Biotechnology Advances等杂志SCI引用13次).
18. Zhang, G, Gao, F*: Quantitative analysis of correlation between AT and GC biases among bacterial genomes. PLoS ONE 2017, 12(2):e0171408 (被Nucleic Acids Research等杂志SCI引用21次).
19. Peng, C, Lin, Y, Luo, H and Gao, F*: A comprehensive overview of online resources to identify and predict bacterial essential genes. Frontiers in Microbiology 2017, 8:2331 (被Briefings in Bioinformatics, Bioinformatics等杂志SCI引用37次).
20. Yang, Z-K, Gao, F*: The systematic analysis of ultraconserved genomic regions in the budding yeast. Bioinformatics 2018, 34(3):361-366.(SCI引用2次)
21. Yang, Z-K, Luo, H, Zhang, Y, Wang, B and Gao, F*: Recombinational DSBs-intersected genes converge on specific disease- and adaptability-related pathways. Bioinformatics 2018, 34(20):3421-3426.(新闻报道)
22. Yang, Z-K, Luo, H, Zhang, Y,Wang, B and Gao, F*: Pan-genomic analysisprovides novel insights into the association of E. coli with human host and its minimal genome. Bioinformatics 2019, 35(12):1987-1991 (被Nature Reviews Microbiology等杂志SCI引用23次).
23. Luo, H, Quan, C-L, Peng, C and Gao, F*: Recent development of Ori-Finder system and DoriC database for microbial replication origins. Briefings in Bioinformatics 2019, 20(4):1114–1124(被Trends in Biochemical Sciences、EMBO Journal等杂志SCI引用35次).
24. Gao, F*: Recent developments of software and database in microbial genomics and functional genomics. Briefings in Bioinformatics 2019, 20(2): 732–734.(新闻报道)(SCI引用4次)
25. Luo, H, Gao, F*: DoriC 10.0: an updated database of replication origins in prokaryotic genomes including chromosomes and plasmids. Nucleic Acids Research 2019, 47(D1):D74-D77 (被Annual Review of Microbiology、Genome Research、PLoS genetics等杂志SCI引用62次)(荣获2020全国博士后人工智能发展与应用论坛优秀奖).
26. Quan, C-L, Gao, F*: Quantitative analysis and assessment of base composition asymmetry and geneorientation bias in bacterial genomes. FEBS Letters 2019, 593(9):918-925 (SCI引用2次).
27. Wang, D and Gao, F*: Comprehensive Analysis of Replication Origins in Saccharomyces cerevisiae Genomes. Frontiers in Microbiology 2019, 10:2122 (SCI引用9次).
28. Gao,F*,Leonard, AC*: Editorial: DNA Replication Origins in Microbial Genomes, Volume 2. Frontiers in Microbiology 2019, 10:2416.
29. Bai, L, Zhang, S, Deng, Y, Song, C, Kang, G, Dong, Y, Wang, Y, Gao, F* & Huang, H*: Comparative genomics analysis of Acinetobacter haemolyticus isolates from sputum samples of respiratory patients. Genomics 2020, 112(4):2784-2793 (SCI引用14次).
30. Yan, F, Gao, F*: A systematic strategy for the investigation of vaccines and drugs targeting bacteria. Computational and Structural Biotechnology Journal 2020, 18:1525-1538 (SCI引用15次).
31. Wu, H, Wang, D, Gao, F*: Toward a high-quality pan-genome landscape of Bacillus subtilis by removal of confounding strains. Briefings in Bioinformatics 2021, 22(2):1951-1971 (被Molecular Biology and Evolution、ISME Journal 、Nucleic Acids Research等杂志SCI引用36次).
32. Wang, D, Lai FL, Gao, F*: Ori-Finder 3: a web server for genome-wide prediction of replication origins in Saccharomyces cerevisiae. Briefings in Bioinformatics 2021, 22(3): bbaa182 (SCI引用9次).
33. Luo, H, Lin, Y, Liu, T, Lai, F-L, Zhang, C-T, Gao, F*& Zhang, R*: DEG 15, an update of the Database of Essential Genes that includes built-in analysis tools. Nucleic Acids Research 2021, 49(D1):D677–D686 (被Nature Biotechnology、Genome Medicine、Trends in Biotechnology、Nucleic Acids Research、Biotechnology Advances、JCI Insight 等杂志SCI引用165次,高被引论文).
34. Yan, F, Gao, F*: Comparison of the binding characteristics of SARS-CoV and SARS-CoV-2 RBDs to ACE2 at different temperatures by MD simulations. Briefings in Bioinformatics 2021, 22(2):1122-1136 (被Chemical Reviews、Chemical Society Reviews、Cell Chemical Biology、Research等杂志SCI引用30次). (人民日报)(科技日报)(人民网)(光明网)(联合早报)(鳳凰华人资讯网)(前瞻网)
35. Liu, T, Luo, H*, Gao, F*: Position preference of essential genes in prokaryotic operons. PLoS ONE 2021, 16 (4):e0250380(被Nature Reviews Genetics杂志引用). (SCI引用3次)
36. Pelliciari, S, Dong, M-J, Gao, F* and Murray H*, Evidence for a chromosome origin unwinding system broadly conserved in bacteria, Nucleic Acids Research 2021, 49(13):7525–7536.(新闻报道) (SCI引用9次)
37. Yang, Z-K#*, Pan, L #, Zhang, Y#, Luo, H and Gao, F*, Data-driven identification of SARS-CoV-2 subpopulations using PhenoGraph and binary-coded genomic data, Briefings in Bioinformatics 2021, 22(6):bbab307 (#These authors contributed equally to this work) (荣获2021年度广州市医学会医学优秀学术论文二等奖)(新闻报道) (被Nature Communications、MedComm等杂志SCI杂志引用7次)
38. Yan, F, Gao, F*: An overview of potential inhibitors targeting non-structural proteins 3 (PLpro and Mac1) and 5 (3CLpro/Mpro) of SARS-CoV-2. Computational and Structural Biotechnology Journal 2021, 19:4868-4883 (SCI引用41次,热点文章).
39. Yan, F, Gao, F*: EK1 with dual Q1004E/N1006I mutation: a promising fusion inhibitor for the HR1 domain of SARS-CoV-2, Journal of Infection 2022, 84(4):588-590. (被Signal Transduction and Targeted Therapy等杂志SCI引用5次)
40. Lai, F-L, Gao, F*: GC-Profile 2.0: an extended web server for the prediction and visualization of CpG islands, Bioinformatics 2022, 38 (6):1738-1740. (SCI引用10次)
41. Li, P, Zhang, J, Deng, Z, Gao, F*, Ou, H-Y*: Identification and characterization of a central replication origin of the mega-plasmid pSCATT of Streptomyces cattleya, Microbiological Research 2022, 257:126975.
42. Yang, T, Gao, F*: High-quality pan-genome of E. coli generated by excluding confounding and highly similar strains reveals an association between unique gene clusters and genomic islands, Briefings in Bioinformatics 2022, 23(4): bbac283. (被PNAS等杂志SCI引用11次)
43. Gao, F*, Huang, K*, Xing, Y*: Artificial Intelligence in Omics, Genomics, Proteomics & Bioinformatics 2022, 20(5):811–813. (被GUT、Biomarker Research等杂志SCI引用25次)
44. Dong, M-J#, Luo, H#, Gao, F*: Ori-Finder 2022: A Comprehensive Web Server for Prediction and Analysis of Bacterial Replication Origins, Genomics, Proteomics & Bioinformatics 2022, 20(6):1207-1213. (杂志公众号报道) (被Cell Host & Microbe、Current Biology等杂志SCI引用39次)
45. Dong, M-J#, Luo, H#, Gao, F*: DoriC 12.0: an updated database of replication origins in both complete and draft prokaryotic genomes, Nucleic Acids Research 2023, 51(6):D117–D120. (被Science, Nature Biotechnology, Nature Communications等杂志SCI引用20次)
46. Yan, F, Gao, F*: RBD-ACE2 binding properties in five SARS-CoV-2 variants of concern with new perspectives in the design of pan-coronavirus peptide inhibitors, Journal of Infection 2023, 86(2):e51-e54. (SCI引用5次)
47. Lai, F-L, Gao, F*: Auto-Kla: A novel web server to discriminate lysine lactylation sites using automated machine learning, Briefings in Bioinformatics 2023, 24(2):bbad070.(公众号报道;被Trends in Endocrinology & Metabolism、Cancer Letters、Cell Death & Differentiation等杂志SCI引用44次)
48. Zhong, H-S, Dong, M-J, Gao, F*: G4Bank: A database of experimentally identified DNA G-quadruplex sequences, Interdisciplinary Sciences: Computational Life Sciences 2023, 15(3):515–523.(杂志公众号报道) (被Nucleic Acids Research、Genome Research、Journal of Big Data等杂志SCI引用8次)
49. Sun, B, Gao, F*: Investigation of escape mechanisms of SARS-CoV-2 Omicron sub-lineages and exploration of potential antibodies for XBB.1, Journal of Infection 2023, 87(4):354-357.
50. Perez-Rueda, E*, Gao,F*: Editorial: Insights in Evolutionary & Genomic Microbiology: 2022. Frontiers in Microbiology 2023, 14:1269933.
51. Lai, F-L, Gao, F*: LSA-ac4C: A hybrid neural network incorporating double-layer LSTM and self-attention mechanism for the prediction of N4-acetylcytidine sites in human mRNA, International Journal of Biological Macromolecules 2023, 253:126837. (SCI引用17次)
52. Liang, Y-T, Luo, H, Lin, Y, Gao, F*: Recent advances in the characterization of essential genes and development of a database of essential genes, iMeta 2024, 3(1):e157.(杂志公众号报道) (被Drug Discovery Today等杂志SCI引用9次)
53. Yin, Z-N#, Lai, F-L#, Gao, F*: Unveiling human origins of replication using deep learning: accurate prediction and comprehensive analysis, Briefings in Bioinformatics 2024, 25(1):bbad432. (SCI引用4次)
54. Zhao, X, Gao, F*: Novel Omicron Variants Enhance Anchored Recognition of TMEM106B: A New Pathway for SARS-CoV-2 Cellular Invasion, Journal of Physical Chemistry Letters 2024, 15(3):671-680.(ACS美国化学会公众号报道) (SCI引用4次)
55. Zeng, Y-H, Yin, Z-N, Luo, H*, Gao, F*: DeOri 10.0: An Updated Database of Experimentally Identified Eukaryotic Replication Origins, Genomics, Proteomics & Bioinformatics 2024, 22(5):qzae076.(杂志公众号报道)
56. Geng, Y-Q, Lai, F-L, Luo, H*, Gao, F*: Nmix: A hybrid deep learning model for precise prediction of 2'-O-methylation sites based on multi-feature fusion and ensemble learning, Briefings in Bioinformatics 2024, 25(6):bbae601. (SCI引用2次)
57. Zhao, X, Gao, F*: Dynamic Mechanism of Norepinephrine Reuptake and Antidepressants Blockade Regulated by Membrane Potential, Journal of Chemical Theory and Computation 2025, 21 (5):2780-2797.
58. Li, Y, Gao, F*: OriV-Finder: a comprehensive web server for bacterial plasmid replication origin analysis. Nucleic Acids Research, 2025, 53 (W1):W451–W456.
59. Cao, S#, Sun, B#, Gao, F*: From Immune Evasion to Broad In Silico Binding: Computational Optimization of SARS-CoV-2 RBD-Targeting Nanobody. Frontiers in Immunology, 2025, 16:1637955.
60. Zhao, X, Gao, F*: Rocker-Switch Mechanism of Choline Transmembrane Transport in FLVCR2: Dynamic Latch Residues and Cooperative Regulation of Transmembrane Helices. JACS Au, 2025, 5(10):4936–4955.
61. Geng, Y-Q, Luo, H*, Gao, F*: AIPred: comprehensive prediction and analysis of non-histone acetylation via protein language model and interpretable machine learning, BMC Biology 2025, 23, 311.
Publication as First Author:
1. Gao, F, Ou, H-Y, Chen, L-L, Zheng, W-X, Zhang, C-T: Prediction of proteinase cleavage sites in polyproteins of coronaviruses and its applications in analyzing SARS-CoV genomes. FEBS Letters 2003, 553(3):451-456.(央视新闻报道)(科技日报)(教育部网站)(人民日报)(中国青年报)(科学时报)(被Chemical Reviews, JACS, ACS Catalysis, Journal of Virology (?9)? 等杂志SCI引用75次)
2. Gao, F, Zhang, C-T: Comparison of various algorithms for recognizing short coding sequences of human genes. Bioinformatics 2004, 20(5):673-681.(被Genome Research、eLife、MBE等杂志SCI引用53次,论文还多次被Duke University, MIT等国际知名高校的学位论文所引用)
3. Gao, F, Zhang, C-T: GC-Profile: a web-based tool for visualizing and analyzing the variation of GC content in genomic sequences. Nucleic Acids Research 2006, 34(W1):W686-W691(被Nature Reviews Microbiology、Nature Microbiology、Nature Communications、PLoS Biology等杂志SCI引用130次,论文还被Springer、Cambridge University Press等出版社的14本英文专著所引用).
4. Gao, F, Zhang, C-T: Isochore structures in the chicken genome. FEBS Journal 2006, 273(8):1637-1648 (SCI引用6次).
5. Gao, F, Zhang, C-T: DoriC: a database of oriC regions in bacterial genomes. Bioinformatics 2007, 23(14):1866-1867 (被Nature、Seminars in Cancer Biology、FEMS Microbiol Rev 等杂志SCI引用74次).
6. Gao, F, Zhang, C-T: Origins of replication in Cyanothece 51142. Proc Natl Acad Sci USA 2008, 105(52):E125 (被Current opinion in microbiology等杂志SCI引用15次).
7. Gao, F, Zhang, C-T: Prediction of replication time zones at single nucleotide resolution in the human genome. FEBS Letters 2008, 582(16):2441-2444.
8. Gao, F, Zhang, C-T: Origins of replication in Sorangium cellulosum and Microcystis aeruginosa. DNA Research 2008, 15(3):169-171 (SCI引用5次).
9. Gao, F, Zhang, C-T: Ori-Finder: A web-based system for finding oriCs in unannotated bacterial genomes. BMC Bioinformatics 2008, 9:79 (曾入选ESI高被引论文,被Cell、Nature、Nature Microbiology、Nature Reviews Methods Primers、Cell Host & Microbe、The ISME Journal、PNAS 等杂志SCI引用230次).
10. Gao, F, Wang, Y, Liu, Y-J, Wu, X-M, Lv, X, Gan, Y-R, Song, S-D, Huang, H: Genome Sequence of Acinetobacter baumannii MDR-TJ. Journal of Bacteriology 2011, 193(9):2365-2366 (被Nature Communications等杂志SCI引用23次).
11. Gao, F, Zhang, RR: Enzymes are enriched in bacterial essential genes. PLoS ONE 2011, 6(6):e21683 (SCI引用15次).
12. Gao, F#, Lin, Y#, Zhang, RR: RNA-DNA differences are rarer in proto-oncogenes than in tumor suppressor genes. Scientific Reports 2012, 2:245 (#These authors contributed equally to this work) (SCI引用2次).
13. Gao, F, Luo, H, Zhang, C-T: DeOri: a database of eukaryotic DNA replication origins. Bioinformatics 2012, 28(11):1551-1552 (被Molecular Cell、Cell Reports等杂志SCI引用31次).
14. Gao, F, Luo, H, Fu, Z, Zhang, C-T, Zhang, R: Exome sequencing identifies novel ApoB loss-of-function mutations causing hypobetalipoproteinemia in type 1 diabetes. Acta Diabetologica 2015, 52(3):531-537.
15. Wei, W#, Gao, F#, Du, M-Z, Hua, H-L, Wang, J, Guo, F-B: Zisland Explorer: detect genomic islands by combining homogeneity and heterogeneity properties. Briefings in Bioinformatics 2017, 18(3):357-366 (#These authors contributed equally to this work) (被FEMS Microbiology Reviews等杂志SCI引用38次).
Book:
1. Gao F, Luo H, Zhang CT, Zhang R*. (2015) Gene Essentiality Analysis Based on DEG 10, an Updated Database of Essential Genes. In: Lu L. (eds) Gene Essentiality. Methods in Molecular Biology, vol 1279. Humana Press, New York, NY. https://doi.org/10.1007/978-1-4939-2398-4_14 (被Nature Reviews Genetics、Nature Communications等杂志SCI引用33次).
2. Wu H, Yang ZK, Yang T, Wang D, Luo H, Gao F*. (2022) An Effective Preprocessing Method for High-Quality Pan-Genome Analysis of Bacillus subtilis and Escherichia coli. In: Zhang R. (eds) Essential Genes and Genomes. Methods in Molecular Biology, vol 2377. Humana, New York, NY. https://doi.org/10.1007/978-1-0716-1720-5_21
3. Gao, F ed.: DNA replication origins in microbial genomes. Lausanne: Frontiers Media 2016, doi: 10.3389/978-2-88919-779-8(新闻报道).
4. Gao, F., Leonard, A. C., eds. DNA Replication Origins in Microbial Genomes, Volume 2. Lausanne: Frontiers Media SA 2019. doi: 10.3389/978-2-88963-245-9.